What is xyy in genetics

Men who have 47, XYY syndrome themselves are also not thought to be at an increased risk to have a child with chromosome differences. Some sperm cells of a man with 47, XYY syndrome will have an extra Y chromosome. However, it is thought that these cells are less likely to be able to survive to fertilize an egg. Therefore, the chances for a man with 47, XYY syndrome to have a child with a sex chromosome abnormality are not thought to be increased.

Diagnosis Diagnosis. A doctor may then order testing to see if there is a genetic explanation for the signs and symptoms. Tests that may be ordered include: [2] Karyotype : a test that is used to view all the chromosomes in a cell Chromosomal microarray : a test that looks for extra or missing chromosomes or pieces of chromosomes In some cases, 47, XYY syndrome may be suspected prenatally based on routine screening tests.

A diagnosis can be confirmed with prenatal tests such as an amniocentesis or chorionic villus sampling CVS. Treatment Treatment. The signs and symptoms of 47, XYY syndrome can be managed with a variety of therapies. Occupational therapy may be recommended for infants and young boys who have low muscle tone hypotonia , and speech therapy may be recommended for boys who have speech delay.

Boys with 47, XYY syndrome may be in special education at school, or they may have extra help in some classes. If autism spectrum disorder is present, applied behavioral analysis ABA therapy may be recommended. Prognosis Prognosis. The long-term outlook for people with 47, XYY is typically good. Boys with this syndrome can do well both in school and in building social relationships. Men with 47, XYY syndrome can also have successful careers and families of their own.

Organizations Organizations. Organizations Supporting this Disease. Social Networking Websites. Do you know of an organization? Learn More Learn More. Click on the link above to view this information. This website is maintained by the National Library of Medicine. The Merck Manuals Online Medical Library provides information on this condition for patients and caregivers.

NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them. Click on the link above to view this information page. In-Depth Information The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers.

This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health.

Visit the website to explore the biology of this condition. Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge. PubMed is a searchable database of medical literature and lists journal articles that discuss 47, XYY syndrome. Click on the link to view a sample search on this topic. Submit a new question 47,XYY syndrome was present in my first delivery.

See answer I have a 4 year old son who was diagnosed with XYY karotype about a year ago. See answer Have a question? References References. Genetics Home Reference. Ross J and Bishop D. Lenroot RK. XYY Syndrome. National Organization for Rare Disorders. Oral, physical, and behavioral aspects of patient with chromosome 47, XYY syndrome.

October-December ; 33 4 Clinical aspects of infertile 47,XYY patients: a retrospective study. Human Fertility. Positive effects of early androgen therapy on the behavioral phenotype of boys with 47,XXY.

June ; 2 Do you know of a review article? Share this content:. Close Copy Link. You May Be Interested In. How to Find a Disease Specialist. Tips for the Undiagnosed. Support for Patients and Families. Tips for Finding Financial Aid. Help with Travel Costs. How to Get Involved in Research. Medical and Science Glossaries. A person with XYY syndrome can get help with any learning or developmental delays through speech therapy, occupational therapy, or other assistance.

Because most cases of XYY syndrome are not inherited, and the syndrome occurs randomly in pregnancies of women from all ages and ethnic backgrounds, it cannot be prevented. The closest disorders associated with XYY syndrome are other conditions that include sex chromosome abnormalities, such as Klinefelter syndrome , which is a group of chromosomal disorders in males in which one or more extra X chromosomes are present.

Other disorders that share similar symptoms to XYY syndrome, but have different molecular causes, include:. Reliable health resources can be helpful for finding information and support for XYY syndrome. Many organizations provide educational materials and can help you find doctors who specialize in symptoms related to the syndrome. There are also online communities that offer support as well as practical advice and tips. Here are two we recommend.

Unique , supports, informs and networks with anyone affected by a rare chromosome disorder or an autosomal dominant single gene disorder. By subscribing you agree to the Terms of Use and Privacy Policy. Health Topics. Health Tools. XYY Syndrome.

Reviewed: November 10, Occasionally, the disorder causes significant problems. Some boys also may have delayed development of their social, language, and learning skills. They also can have problems with reading and understanding math, and may have mild delays with coordination. These problems might ease as they get older and reach adulthood.

Otherwise, treatment can help manage these issues. A small number of boys may have increased testicular size for their age, or have an increased risk for asthma and seizures. Many boys with XYY syndrome are healthy and have no obvious symptoms. So sometimes the condition isn't diagnosed or is found when a doctor checks for a different issue. Often, XYY syndrome is found because parents talked with a doctor about concerns with their son's development.

This can help boys receive a diagnosis early. Research has shown that early interventions and treatments are more effective. To diagnosis XYY syndrome, doctors check a blood sample for the extra Y chromosome. Before birth, the condition may be found through karyotype test chromosomal analysis or noninvasive prenatal testing NIPT.

NIPT is done on the fluid surrounding the fetus, tissue from the placenta, or the blood from the mother. After birth, doctors can make a diagnosis with a karyotype or with a microarray test from the baby. Finding services early is important and can greatly increase their ability to help boys live a healthier, more productive life. Options vary greatly depending on how old a boy is at the time of his diagnosis, whether he has noticeable symptoms, and the severity of those symptoms.

Regular doctor visits. At periodic visits, a doctor can monitor a boy's development for delays, social and language disabilities, or health problems and treat these promptly. Educational support services.